Wednesday, October 30, 2019

The Reason Why Public Service Matters Essay Example | Topics and Well Written Essays - 500 words

The Reason Why Public Service Matters - Essay Example Public service benefits society as a whole because everyone gains something out of it. Typically, the people performing public service are on the upper end of the rich scale, while those receiving the services are on the lower end. This does not mean they poorer people do not deserve public service being performed for them—after all, they pay their taxes just like everyone else. In every free and fair society, there are certain conditions that every person needs to live by. Public service can benefit society because the public’s interest is at heart. Public service also matters because it helps those who perform it to feel uplifted. There is no greater feeling that volunteering your time and doing something for someone else for no particular reason. Most likely, the person on the receiving end will feel very grateful for what has been done for them, and the public service doer feels rewarded for their efforts. If people who are performing public service feel appreciated for the work that they are doing, then they will likely help the community again in the future. If everyone participates in public service, then not too much is required of any one individual. Lastly, public service matters because it can really change another person’s life. Very often public service is performed for those who are in need. Even though the task performed for them may not seem like much, it may make a world of difference in the life of the person receiving it. If that person is feeling negative towards the rest of society, then they may rediscover the belief in mankind. This positivity can be applied in other areas of their life and the person can make significant changes. Above all, the person who is receiving the public service may feel compelled to help out someone else in need someday.

Monday, October 28, 2019

Debates on “Standard of Care” in Research

Debates on â€Å"Standard of Care† in Research Current debates on â€Å"Standard of Care† in Research on Human subjects in the Developing World Zoheb Rafique INTRODUCTION: For sometimes now, medical and bioethics communities have been facing some of difficult and divisive issues regarding the ethics of the international research. These issues often get fuel, when the interventional research is conducted on the poor and vulnerable people in the poor developing countries. Normal term â€Å"Standard of the Care†, against which some of new interventions and inventions are tested in the medical research has not been adequately defined. This term is often usually taken to mean the â€Å"best proved treatment† for any of the condition under investigation in any of the trial. The debate regarding what constitutes a reasonable and fair standard of care for subjects in the developing countries and those who participate in the clinical trials has been aroused by the critics of the studies on transmission of HIV. Those critics also argued that the placebo controlled trials of the new regimens as to prevent the vertical transmission of the HIV were hi ghly unethical because of the reason that they included the placebo arm rather than â€Å"best proven treatment† which is available in the developed countries. While some of the commentators considered criticisms to be unbiased and associated with imperialistic attitudes. This debate made it very clear that high standards of the research plans to have not been comprehensively and adequately defined. Although there was some justified concern that the pressure from US food and the drug administration could â€Å"dilute† declaration of the Helsinki, and critics were also confident that whether a trial was ethical could be deduced from text of a declaration. But some declarations such as declaration of the Helsinki, that governing international research ethics are accepted like the constitutions and needing interpretation. Also assuming what is ethical, goes beyond merely following all the prescriptions and also requires some moral reasoning (1). In this article, I will di scuss and comment on various debates on standard of care in human research in the developing world. DISCUSSION Equal standards of medical care during research, reflecting equal respect for the dignity of subjects, could be taken to mean any one or a combination of several requirements. It is arbitrary and not justifiable to select only one of these, for example, which drugs are used to compare the standard of care in developed and developing countries. In context of some disputed studies on the issue of HIV transmission, the forced emphasis on some â€Å"best proven drugs† having greater considerations of whether those drug regimen can be safely applied in the different settings. Also little attention has been paid to fact there were so many differences between the pregnant women in the developing countries, and in countries where â€Å"best proven† treatment previously been established. The pregnant women in the developing countries present to the antenatal clinics at much later in the pregnancy than women in original studies; they are often malnourished and anemic, and they of ten live within some context in which the breast feeding having different implications for the newborn infants. Moreover, the advice don’t breast feed would then contradict years of the intensive education by WHO (World Health Organization). Also concerning use of the placebos, the approach than also been simplistic. A placebo arm is legal and justified in any trial requires some careful consideration of the potential benefits and harms in those specific contexts and they cannot be just simply deduced from any general declaration. And of course it is very necessary to acknowledge the fact that many of the placebo trials are often unethical because they are performed largely for the marketing purposes just to show that â€Å"me too† drugs, have effects and actions greater than those placebo, and rather than to study that they are better than the existing similar, often cheaper, drugs. Also not only should nothing to be done to make it easier to perform such trials, but also each and every effort can be made to reduce and decrease wasting time, money on the â€Å"promotional studies†. In these situations where there are some good reasons for the placebo controlled trials, those should be considered on the merits rather than to be precluded by any bluntly designed clause in the declaration. To protect the host communities from the exploitation, most of the commentators argue that the efforts to improve the health care in developing countries should never ever involve the research that uses and utilizes less than â€Å"Worldwide best† methods, and meaning best of methods available anywhere in this world. Most notably, paragraph 29 of the Declaration of Helsinki states: â€Å"The benefits, risks, burdens, and effectiveness of a new method should be tested against those of the best current prophylactic, diagnostic, and therapeutic methods†. The debate over the issue what standard of the care should be required for the individuals p articipating in the research trials typically focuses on the research conducted in the developing countries by the investigators from the developed countries. This focus makes some sense. Most of the clinical research is conducted by the investigators from the developed countries, and most of communities lacking the access to good health care are located in developing countries. Researchers from the developing countries can also exploit the host communities. And also the communities in the developed countries lack access to best methods available in the world, and increasing the potential of being exploited. Then a complete analysis, should also address the potential for exploitation and independent of nationality of investigators, and the geographic location of any study (2). When the Helsinki calls for â€Å"the best proven therapeutic method† than does it mean [A] â€Å"the best therapy which is available anywhere in world†? Or does it say [B] â€Å"the standard th at is applicable in that country in which drug trial is conducted†? Helsinki is not very clear about this. But I must say that [1] a detailed and careful analysis of document and also its history tells us that the best therapy standard was intended initially and primarily as the standard of medial practice. This conclusion yields another conclusion: that [2] â€Å"the best proven standard of therapy must necessarily be the standard which prevails in that country in which clinical trial is being carried out. In part, interpretations A and B often differ over what I call the question of relevant reference point. Also emphasizing this disagreement makes it appear as the dispute hinges on question of whose medical practice constitutes relevant medical practice. So, the sides of the debate are divided into the proponents of local standard of care and also the critics who often champion the global standard of care. Framing the debate as the question of relevant reference point, how ever, effectively obscures a more fundamental source of disagreement. To see this, consider a crucial assumption that lies behind following argument. It is sometimes claimed that (1) because content of the standard of care is often fixed by local reference point and (2) because the prevailing treatment for preventing the maternal-infant HIV transmission in those countries where short-course AZT trials were conducted was no treatment at all, that (3) use of the placebo does not fall below established standard of care. Also it is important to see, however, that in order for (3) to follow from (1) and (2), we have to adopt the local reference point for standard of care (3). The ethics of the placebo-controlled trials to prevent the perinatal transmission of the HIV infection in continents like Asia and Africa have been widely debated. Some critics have argued that it is very unethical to leave the patients untreated when the proven life-saving treatment and therapy is being used in oth er parts of the world. We note, that conduct of the placebo-controlled trials in any developed country which would be unethical in some other developed country, has evoked some of furor that surrounded HIV perinatal transmission trials. The patients on other hand can choose not to take part in the trials. Reluctance to participate in the trail may be greater when there is some placebo control and the patients are asked to delay and forgo known effective therapy, also large number of the patients regularly agrees to take part in the placebo-controlled trials of the new agents. The perceived scientific value of the trial can contribute to this decision. Although care must be taken to ensure that manipulation of such considerations (e.g., by exaggerating scientific importance of trial), it seems very reasonable to allow the potential study participants to balance these benefits against some potential risk of the participation in this trial (4). Some of the observers noted more than dec ade ago that the research was conducted in the developing countries without the concern for the adherence of international ethical principles regarding the human subject’s research contained in 1947 Nuremberg code and also in the 1964 Declaration of the Helsinki. This situation has not improved. As for example, two years back, Food and Drug Administration decided that the research studies submitted to it for the review purpose need no longer be bound by Declaration of Helsinki and they must follow only the industry-sponsored Guidelines for the good clinical practice also outlined by International conference on the Harmonization. What is the legal status of Nuremberg code and Declaration of the Helsinki? Are they old outdated ethical rules that the researchers might ignore with the impunity? The question remains open, but just as clinical trials attempting to interrupt mother-to-child transmission of HIV in mid-1990s gave rise to some continuing debate about the global standar ds of care and also benefit sharing, so another mid-1990s research trial in the continent Africa has brought the international research rules back to the center stage (5). In addition to discussing recent debate and concerning international HIV research, also we should focus on whether or not to randomized, as the controlled trials must be conducted for the researchers to learn about intervention’s efficacy. The choice of the study design is not between ethically questionable perfect trials that produce the complete knowledge versus the imperfect designs that produce no knowledge. Moreover designs, such as the observational studies, that resolve the certain ethical quandaries are not necessarily free of the other ethical problems. One problem is that these studies can provide only limited guidance for the public health policy. The other issue is of informed consent, which is one of corner-stones of the research ethics. The quality of the informed consent is compromised when t he potential patient participants believe, wrongly, that the medical care is contingent on their agreeing to participate in the research. Also it is important to emphasize the potential participants that neither their access to the medical care, nor quality of care they receive, will be affected in any of the respect by their decision. It is sometimes very difficult to clarify this separation of the research from the medical care; the potential participants can be made aware through the effective communication that the decision about the research has no implications for their medical interests. Some more challenging situation occurs when the potential participants rightly believe that the medical care is contingent on their agreeing to enroll in the research (6). CONCLUSION The concept of standard of care has prominently figured in the recent controversies over use of placebos in design of the randomized controlled trials conducted in United States and the developing countries as well as the control group selection in critical care RCTs conducted in the United States. The traditional understanding of standard of care to which the physicians are held responsible refers to the typical practice of physicians in professional community. To answer the clinically valuable questions, it is often necessary for the clinical trials to randomize the subjects to interventions that deviate from standard of care in the medical practice. Nevertheless, the control groups that represent standard of care are mostly required to promote clinical value of the randomized trials and also to protect the research subjects. In case of the critical care trials, question whether RCTs should include a control group raises some complex scientific and also ethical issues that call for the careful assessment and judgment (7). In conclusion it is stated that every medical research project involving human subjects should be preceded by careful assessment of predictable risks and burdens in comparison with foreseeable benefits to the subjects or to others. REFERENCES: Solomon R Benatar, Peter A Singer. A new look at international research ethics. BMJ. 2000; Vol. 321, 824-826. David Wendler Et Al. The Standard of Care Debate: Can Research in Developing Countries Be Both Ethical and Responsive to Those Countries’ Health Needs? American Journal of Public Health. 2004; Vol. 94, No. 6, 923-928. Alex John London. The Ambiguity and the Exigency: Clarifying ‘Standard of Care’ Arguments in International Research. Journal of Medicine and Philosophy. 2000; Vol. 25, No. 4, 379-397. Susan S. Ellenberg, and Robert Temple. Placebo-Controlled Trials and Active-Control Trials in the Evaluation of New Treatments. Annals of Internal Medicine. 2000; Vol. 133, No. 6, 464-470. George J. Annas, J.D. Globalized Clinical Trials and Informed Consent. N ENGL J MED. 2009; 360; 20, 2050-2053. Ruth Faden, Nancy Kass. Editorial: HIV Research, Ethics, and the Developing World. American Journal of Public Health. 1998; Vol. 88, No. 4, 548- 550. Franklin G. Miller and Henry J. Silverman. The Ethical Relevance of the Standard of Care in the Design of Clinical Trials. American Journal of Respiratory and Critical Care Medicine. 2004; Vol. 169, 562-564.

Friday, October 25, 2019

Analysis of Proverbs 31 Essay -- The Worthy Woman

The â€Å"Worthy Woman;† what a title. Everyone who has some knowledge of the Bible has heard this phrase. Almost anyone can name some catchy phrase or saying that is from the Bible whether it is from the Psalms or Proverbs or any other book. We all know those verses that tend to get stuck in our mind. However catchy they may be, unless one actually comes to an understanding of what is being said and applies it to their lives, these catchy phrases can just be surface knowledge. Every Christian can get caught in that trap. When someone is considering a Bible passage they should try to learn everything they can about that passage; any background information, what certain words mean, who the author is. The knowledge one can gain from the Bible is never ending. Another problem when studying the Bible is when people use their â€Å"knowledge† of the Bible to make themselves look like better Bible students. The Pharisees were constantly doing this. We need to not be puffed up about the knowledge we gain from the Bible and constantly try to be gaining more and share it with others. Going back to â€Å"the worthy woman,† it is one of the most well known passages and therefore a lot of knowledge and wisdom can be gleaned from it. This is the last chapter of the Proverbs and is divided into two sections. Verses 1-9 are categorized as ‘The Words of King Lemuel,’ followed by verses 10-31 categorized as ‘The Woman Who Fears the Lord.’ This Proverb has a title unlike some of the other Proverbs. This title tells who wrote it and what the proverb is. The title of Proverbs 31 is â€Å"The words of King Lemuel. An oracle that his mother taught him (ESV).† The exact identity of King Lemuel is unknown. Many commentaries suggest that even though ... ... passage because it gives me something to strive for as a woman. It is easy to understand and practical. To have this woman as an example of what a virtuous godly woman should be like, should give us no excuse to not continually strive to be like her in any and every way. We should try to dwell on these qualities and put them into our lives, until those qualities become our lives and we are praised for the good we are doing. Works Cited Arnot, William. "Proverbs 31." Studies in Proverbs: Laws from Heaven for Life on Earth. Grand Rapids, MI: Kregel Publications, 1978. 570-83. Print. Greenstone, Julius H. "Poverbs 31." The Holy SScriptures: Proverbs. Philadelphia: Jewish Pub. Soc. of America, 1950. 329-39. Print. Henry, Matthew. "Proverbs 31." Matthew Henry's Commentary on the Whole Bible. Vol. III. McLean, Virg.: MacDonald, 1991. 971-77. Print. Analysis of Proverbs 31 Essay -- The Worthy Woman The â€Å"Worthy Woman;† what a title. Everyone who has some knowledge of the Bible has heard this phrase. Almost anyone can name some catchy phrase or saying that is from the Bible whether it is from the Psalms or Proverbs or any other book. We all know those verses that tend to get stuck in our mind. However catchy they may be, unless one actually comes to an understanding of what is being said and applies it to their lives, these catchy phrases can just be surface knowledge. Every Christian can get caught in that trap. When someone is considering a Bible passage they should try to learn everything they can about that passage; any background information, what certain words mean, who the author is. The knowledge one can gain from the Bible is never ending. Another problem when studying the Bible is when people use their â€Å"knowledge† of the Bible to make themselves look like better Bible students. The Pharisees were constantly doing this. We need to not be puffed up about the knowledge we gain from the Bible and constantly try to be gaining more and share it with others. Going back to â€Å"the worthy woman,† it is one of the most well known passages and therefore a lot of knowledge and wisdom can be gleaned from it. This is the last chapter of the Proverbs and is divided into two sections. Verses 1-9 are categorized as ‘The Words of King Lemuel,’ followed by verses 10-31 categorized as ‘The Woman Who Fears the Lord.’ This Proverb has a title unlike some of the other Proverbs. This title tells who wrote it and what the proverb is. The title of Proverbs 31 is â€Å"The words of King Lemuel. An oracle that his mother taught him (ESV).† The exact identity of King Lemuel is unknown. Many commentaries suggest that even though ... ... passage because it gives me something to strive for as a woman. It is easy to understand and practical. To have this woman as an example of what a virtuous godly woman should be like, should give us no excuse to not continually strive to be like her in any and every way. We should try to dwell on these qualities and put them into our lives, until those qualities become our lives and we are praised for the good we are doing. Works Cited Arnot, William. "Proverbs 31." Studies in Proverbs: Laws from Heaven for Life on Earth. Grand Rapids, MI: Kregel Publications, 1978. 570-83. Print. Greenstone, Julius H. "Poverbs 31." The Holy SScriptures: Proverbs. Philadelphia: Jewish Pub. Soc. of America, 1950. 329-39. Print. Henry, Matthew. "Proverbs 31." Matthew Henry's Commentary on the Whole Bible. Vol. III. McLean, Virg.: MacDonald, 1991. 971-77. Print.

Thursday, October 24, 2019

Examining the Use of Social Media and Its Impact on Corporate

Title Examining the Use of Social Media and Its Impact on Corporate Commerce Assessment A, Part One – Evaluating the Pros and Cons of Different Social Media Sites Identify the pros and cons for each site. Blogger Con: Security – possible transmission of untrustworthy links Blogger Con: Too much information – public disclosure Blogger Con: Ability to post relevant, up-to-the-minute news and updates Blogger Pro: Ability to create a community Blogger Pro: Ability to incorporate elements of other social media sitesBlogger Pro: Mass customization – widespread use among target audience Blogger Pro: Ability to receive instant feedback from product demographics Digg Con: Not relevant to the niche audience Digg Con: Ability to receive instant feedback from product demographics Digg Con: Mass customization – widespread use among target audience Digg Con: Instant communication to large groups Digg Pro: Media convergence – showing text, screen shots, vid eos Facebook Con: Limited visual presentation of productFacebook Con: Ability to filter comments via an approval mechanism Facebook Con: Security – possible transmission of untrustworthy links Facebook Pro: Ability to create a community Facebook Pro: Ability to incorporate elements of other social media sites Facebook Pro: Mass customization – widespread use among target audience Facebook Pro: Instant communication to large groups Facebook Pro: Ability to receive instant feedback from product demographics Facebook Pro: Mobility – viewing on a cell photo adds to the audienceFacebook Pro: Ability to post relevant, up-to-the-minute news and updates Facebook Pro: Media convergence – showing text, screen shots, videos Flickr Con: Limited access from target audience Flickr Con: Ability to receive instant feedback from product demographics Flickr Con: Mass customization – widespread use among target audience Flickr Pro: Not a good way to build buzz in the beginning Flickr Pro: Limited visual presentation of product Metacafe Con: Ability to receive instant feedback from product demographicsMetacafe Con: Instant communication to large groups Metacafe Con: Ability to receive instant feedback from product demographics Metacafe Pro: Media convergence – showing text, screen shots, videos Twitter Con: Ability to filter comments via an approval mechanism Twitter Con: Character Limits Twitter Con: Limited visual presentation of product Twitter Con: Security – possible transmission of untrustworthy links Twitter Con: Ability to receive instant feedback from product demographics Twitter Pro: Instant communication to large groupsTwitter Pro: Mobility – viewing on a cell photo adds to the audience Twitter Pro: Ability to post relevant, up-to-the-minute news and updates Twitter Pro: Ability to receive instant feedback from product demographics YouTube Con: Ability to filter comments via an approval mechanism YouTube Con: Secu rity – possible transmission of untrustworthy links YouTube Pro: Ability to incorporate elements of other social media sites YouTube Pro: Mass customization – widespread use among target audience YouTube Pro: Media convergence – showing text, screen shots, videosAssessment A, Part Two – Examining the Use of Social Media and its Impact on Corporate Commerce Recommend which social media site Master Dynasty should be launched on. Blog, Twitter, and Facebook. Assessment B – Examining the Use of Social Media and its Impact on Corporate Commerce How can social media sites help us build our brand? Centralizing social site, and create links to our other sites will build up our brand. How can we best reach our target audience? Gather our quality followers instead of quantity, we can choose our niche in our target audience based on profiles.How can it help our corporate commerce to show our audience that we're human beings? Show audience we are not just here to sell, but are gamers to. How does social media help give people a reason to buy from us? Targeting relevant customers and marketing our brand turns selling into participating online community. How can we use customer comments to improve our corporate commerce? By helping, us keep our customers happier by responding to their individual needs after receiving instant feedbacks of comments and posts. Â © 2011 Toolwire, Inc. All rights reserved.

Wednesday, October 23, 2019

The Renaissance as a Distinct Period of Time

The Renaissance as a Distinct Period of Time The Middle Ages was a time in history where everyone was faithful to religion as well as others. Also, in the Middle Ages, people were encouraged to always try their best; they were encouraged to fight for the highest achievement possible and to never give up. The Renaissance, however, was more focused on becoming matured and finding a way to be successful at everything one does. During this era, people fought to become all-sided men, also known as; renaissance men.This means they are not only successful in one type of art but in all types of art, as well as math, science, and literature. The Renaissance was a distinct period in time that was separated from the Middle Ages and began a new era. The writers and thinkers of the fifteenth and sixteenth centuries believed that they took part in a completely different era than the Middle Ages. They believed that they were part of a more modern and current era known as the Renaissance. These peop le considered the Renaissance to be a new beginning of the Middle Ages (Ferguson Doc. 1).Renaissance means †rebirth† in french, which means is a whole new period of time. The art and literature of the Renaissance offered a â€Å"rebirth† of hope, and interest in life and how it was represented. During the Renaissance, religion was seen through a new perspective, the renaissance men found the scientific answers that were against the church heresies. Kepler, an astronomer, used observation and mathematics to prove his thesis. He did not accept what he was told by the church or the ancients. Instead, he proved his theories (Document 7). People were expanding their horizons, art and science was in full splendor.The philosophy of humanism also came about. The middle ages areknown for being limited in their artistic ideas because humans weren't supposed to practice many hobbies of the flesh. The renaissance men wanted to be unique, to stand out, to be different and make an impression on others. Da Vinci, a complex man of the renaissance was interested in anatomy and the realistic portrayal of the human body. He was the ideal man of the renaissance due to his many talents and interests (document 6). During the renaissance, protestantism came about and their churches were much more simplistic.Although catholic and orthodox churches were still stereotypically adorned heavily. The renaissance men were interested and concerned with things of this world, unlike believers, and leaders of the church, who were concerned about heaven. Burchhardt identified a difference between the medieval man, who was controlled by faith throughout his life, and the renaissance man, who fought for the highest individual development (Document 2). The beginning of the Renaissance in the mid-fourteenth century was marked by a turn from medieval life and values dominated by the Church toward the philosophical principles of humanism.The Renaissance was a distinct period in time that was separated from the Middle Ages and began a new era. It was during this time that literacy started to become more widespread and that art really started to take form. Paintings became more realistic, and elements created by the Greeks and the Romans were brought back into paintings; society began to organize itself in a similar way to how it works today. Knowledge and writings that were common to the Greeks and Romans that had lost their importance to the Europeans during the Middle Ages were restored in the Renaissance.